3-D Magnetic Measurement of Neuromagnetic Response of Somatosensory Area to Different Repetition Frequencies

Abstract

3-D magnetic measurements of the bilateral somatosensory evoked fields (SEFs) by electric stimulus to the right thumb for four normal subjects were carried out, using a three-dimensional (3-D) second-order gradiometer connected to 39-channel SQUIDs, which can detect magnetic field components perpendicular to the scalp (Br) and tangential to the scalp (Bθ, Bφ) simultaneously. To discuss the relationship between the phase lag and stimulus repetition frequency (SRF), the delay times of a component synchronous with the SRFs (1.99 to 27.02 Hz) were calculated by the convolution of the reference signal and the SEF wave (BPF: 15-40Hz). The phase lag characteristic to the SRF in the contralateral hemisphere to the stimulus was linear in the ranges below 8 Hz and above 8 Hz in all magnetic components. The phase lag characteristic of the ipsilateral hemisphere to the stimulus was linear in only below-8 Hz in all components. It was tested for significance of the linear regression slope (β ≠ 0, P